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Figure 2 Representative histologic sections of the right atrial free wall from each group (Masson trichrome stain) from a sham dog (A), a fifth week rapid pacing dog (B), and a fifth week rapid pacing with candesartan treated dog (C). In the sham dog, the intracellular space appeared normal. In the control dog, extensive interstitial fibrosis, evidenced by Masson trichrome stain, was found. In the candesartan treated dog, interstitial fibrosis was attenuated. Magnification: x400.