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Figure 1 Median change in 6-min walking distance from baseline to months 3, 6, 9, and 12 in the placebo and beraprost sodium (BPS) groups; p = 0.010 at 3 months; p = 0.016 at 6 months; p = 0.098 at 9 months; and p = 0.180 at 12 months (adjusted for center, etiology, and baseline peak oxygen consumption, 6-min walk, Borg dyspnea score, and vasodilator use). Worst rank for all missing data.