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Figure 2 The decline in end-diastolic volume index following atropine at similar heart rates (94 ± 2 old vs. 96 ± 2 young, p = ns) and diastolic filling periods (340 ± 13 ms old vs. 349 ± 15 ms young, p = ns) was nearly fivefold greater in the old than in the young (–11.6 ± 1.6 ml/m2 old vs. –2.4 ± 1.6 ml/m2 young, p = 0.04).