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Figure 3 Atherosclerotic lesion area. Selective cyclooxygenase-2 inhibition consistently increased lesion size: by 84% in the noninfected group, and by 70% and by 80% in the cytomegalovirus (CMV)-infected low-dose and high-dose groups respectively. In this study, infection with CMV did not increase lesion size. *p = 0.013 vs. no drug treatment/no inoculum group; #p < 0.01 vs. no drug treatment/no inoculum group; p < 0.01 vs. no drug treatment/sham infection group; &p = 0.02 vs. no drug treatment group/CMV infection group; p = 0.05 vs. no drug treatment group/CMV infection group.