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Figure 1 Time course of the activation recovery interval (ARI) before and during ischemia. (A) ARIs in control (open circles), nicorandil (solid circles), 5-hydroxydecanoate (5-HD) (open triangles), and 5-HD + nicorandil (solid triangles) groups. (B) ARIs in HMR1098 (open squares) and HMR1098 + nicorandil (solid squares) groups. Open and solid circles are the same as those in A. *p < 0.05 vs. control; #p < 0.05 vs. nicorandil. Base = baseline; Tx = drug treatment.