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Figure 2 Mean ± SEM plasma urocortin, arginine vasopressin, adrenocorticotrophic hormone (ACTH), and cortisol responses to incremental boluses of urocortin and a vehicle control in eight normal sheep (left panel) and eight heart failure sheep (right panel). Significant differences are shown by: *p < 0.05; **p < 0.01; p < 0.001.