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Figure 2 Echocardiographic changes over time. (A) Least squares mean (LSM) change (±SEM) from baseline in left ventricular ejection fraction (%). (B) LSM change from baseline in left ventricular internal diastolic diameter/body surface area (cm/m²). The p values refer to the LSM comparison between the valsartan (solid bars) and placebo (open bars) groups by analysis of co-variance. n = total number of patients in the valsartan and placebo treatment groups.