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Figure 1 ROC curves of biochemical markers for the primary end point (A) and cutoff points for CRP (B) or Lp(a) (C). ROC area was 0.77; 95% CI 0.70 to 0.83; p < 0.001, ROC area 0.67; 95% CI 0.60 to 0.72; p < 0.001, ROC area 0.51; 95% CI 0.44 to 0.59; p = 0.71 for CRP, Lp(a) and tHCY, respectively. CRP = C-reactive protein; Lp(a) = lipoprotein(a); Se = sensitivity; Sp = specificity; tHCY = total homocysteine.