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Figure 2 An example of the histology slide in a rabbit heart that received 60-min coronary occlusion and five days of reperfusion. The infarcted region consisted of central core of coagulation necrosis (C) and an organized zone (i.e., granulation tissue [G]) surrounding the core of necrosis (hematoxylin-eosin staining). The organized zone (G) and total infarct area (i.e., G plus C) were measured by NIH image, and the volume of the organized zone expressed as a percentage of total infarct size was calculated for each heart as an index of the extent of infarct healing. N = noninfarcted myocardium.