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Figure 2 Estimated net release of tissue-type plasminogen activator (t-PA) antigen (solid lines) and activity (dashed lines) during bradykinin (right) and substance P (left) infusions in the presence (solid circles) or absence (open circles) of angiotensin-converting enzyme (ACE) inhibition. p < 0.01 by analysis of variance (ANOVA) for all responses. *p < 0.001 by ANOVA for long-term ACE inhibition versus no ACE inhibition.