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Figure 1 Effect of intra-arterial bradykinin and substance P infusions on blood flow and plasma tissue-type plasminogen activator (t-PA) antigen (solid lines) and activity (dashed lines) concentrations in the infused (solid symbols) and noninfused (open symbols) arms in the presence (left) or absence (right) of angiotensin-converting enzyme (ACE) inhibition. *p < 0.05 by analysis of variance (ANOVA). p < 0.001 by ANOVA for long-term ACE inhibition versus no ACE inhibition.