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Figure 2 Ambulatory ECG monitoring during phase 2 (monotherapy). Both amlodipine and diltiazem (Adizem XL) reduced ischemic events, but there was a significantly better effect in the amlodipine-treated patients after omission of a single drug dose (see text). *p < 0.002 between amlodipine and diltiazem (Adizem XL) withdrawal.