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Figure 1 The open artery trial protocol. *Two patients meeting the angiographic criteria were excluded on account of distal left anterior descending (LAD) occlusion with target vessel diameter <2.5 mm. Randomization was based on the principle of minimization of confounding baseline variables (see text). MI = myocardial infarction; PCI = percutaneous coronary intervention; TOAT = Open Artery Trial.