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Figure 1 Mean (± SEM) number of microbubbles retained within the cremasteric microcirculation of wild-type and C3-deficient (C3–/–) mice after injection of 3 x 107 microbubbles. *p < 0.01 all other microbubbles in wild-type mice; {dagger}p < 0.01 vs. MBneg in wild-type mice. MBneg = lipid microbubbles with a net negative charge; MBneut = lipid microbubbles with a net neutral charge; PEG = polyetheleneglycol.