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Figure 1 Effect of acetylcholine and nitroglycerin (NTG) on percent change in volumetric coronary blood flow in both groups. Solid diamond = baseline; solid square = follow-up. *p = 0.15 for the difference between baseline and follow-up at maximal dosage of acetylcholine (placebo group). **p < 0.05 for the difference between baseline and follow-up at the maximal dosage of acetylcholine (folic acid/cobalamin group). p < 0.005 for the difference at baseline and follow-up between the placebo group and the folic acid/cobalamin group with the general linear model.