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Figure 1 Tissue Doppler image in the apical four-chamber view of a normal subject (upper left panel). (Right panel) The velocity profile during one cardiac cycle obtained at the base of the interventricular septum. The solid lines mark the duration of systole (310 ms), and the arrow indicates the peak systolic velocity (8 cm/s). The diastolic filling of the LV is reflected in the E-wave (E) and A-wave (A). (Lower left panel) Tissue tracking displays, in color-coded format, the regional myocardial shortening (mm) in each segment, calculated automatically as the integral of the digitally stored velocity tracing in systole in each segment.