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Figure 2 The prevalence of hypertension (HT), hypercholesterolemia (HC), obesity and cigarette smoking at the time of the event in 163 patients with familial premature coronary artery disease (P-CAD) (solid bars), 326 age- and gender-matched patients with sporadic (nonfamilial) P-CAD (hatched bars) and 489 age- and gender-matched individuals randomly sampled from the local general population (open bars). Hypertension was defined as blood pressure 
160/95 mm Hg and/or prescription of antihypertensive agents; hypercholesterolemia corresponded to plasma total cholesterol levels 6.5 mmol/l and/or prescription of lipid-lowering agents; obesity was defined as a body mass index 30 kg/m2; and smoking corresponded to active cigarette smoking at the time of diagnosis or within the preceding five years. *p < 0.05; **p < 0.01; ***p < 0.001.