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Figure 3 (Upper) Anterior wall microvascular permeability index at baseline and in response to intravenous adenosine in the three experimental groups. (Lower) Relative change of anterior wall microvascular permeability index in response to intravenous adenosine in the three experimental groups (compared to baseline). HC = hypercholesterolemic pigs; HC+S = hypercholesterolemic pigs receiving simvastatin; N = normocholesterolemic pigs. *p < 0.001 vs. N and HC+S.