Click on image to view larger version.

Figure 1 Diurnal variation of the total myocardial ischemic episodes in all patients with variant angina (A) and that of the mean myocardial ischemic episodes in each patient (B). The frequency of ischemic episodes was highest from midnight to morning (00:00 to 08:00) and was lowest from morning to late afternoon (08:00 to 16:00). The frequency from late afternoon to midnight was higher than that from morning to late afternoon (16:00 to 00:00). *p < 0.01 vs. from midnight to morning (00:00 to 08:00). See text for details. 00:00 = midnight; 08:00 = 8 AM; 16:00 = 4 PM.