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Figure 4 Receiver operator characteristic curves for target lesion revascularization (TLR) as a function of severity of angiographic restenosis (A = any reported TLR; B = adjudicated TLR). An area under the curve approaching 1.0 represents optimal discrimination for the measure of interest (follow-up diameter stenosis [DS]). A result in the upper left hand corner of the graph would indicate a perfect cutoff value with maximum sensitivity and specificity. As shown in A and B, the cutoff value of 50% DS best represents this position.