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Figure 8 Immunohistochemical analysis of myxoid tissue in atherectomized human coronary stent neointima at two months after stenting. In modified Movat’s staining, this specimen is composed of two different kinds of tissue: one is the myxoid tissue (labeled as M) enriched in blue-colored proteoglycans, and the other is collagen-rich cell-depleted area (labeled as C). Both versican and hyaluronan are abundant in this myxoid tissue, whereas both molecules are spared in the collagen-rich cell-depleted area. Perlecan staining shows labeling around the stellate-shaped smooth muscle cells. Transforming growth factor-ß1 staining shows cytoplasmic labeling in the stellate cells. Counterstaining with either methylgreen or hematoxylin. Bar = 100 µm.