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Figure 4 Typical photomicrographs of noninfarct tissue six weeks after myocardial infarction. Picrosirius-red staining shows collagen as red, and myocytes and other structures as yellow. A2, B2 = polarized light showing collagen as bright yellow or green; A1, A2 = placebo effect; B1, B2 = effect of amlodipine, showing a resistance vessel with an increased area of media, relative to the lumen, and perivascular fibrosis. Arrows indicate vessels. Crystalline material from postmortem arteriograms are seen within the lumen.