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Figure 1 Results of measurement of tissue inhibitor of matrix metalloproteinase (TIMP) activity in left ventricular extracts of Dahl salt-sensitive (DS) and Dahl salt-resistant (DR) rats at the left ventricular hypertrophy (LVH) and congestive heart failure (CHF) stages. The TIMP activity was measured by reverse zymography. The data are expressed as arbitrary units (values for 11-week-old DR rats were set at 1.0, and remaining values were adjusted accordingly) and mean values ± SEM (n = 8 per group). *p < 0.01; pa = 0.0113; pt = 0.0005; pi = 0.0018. W = weeks.