Click on image to view larger version.

Figure 6 Western blot showing lamin A and lamin C bands and the additional 30 kDa immunoreacting band corresponding to an abnormal small peptide comprising the epitope recognized by the antibody. This band is identical in patients with different lamin A/C (LMNA) mutations (lane 2: A-II-1; lane 3: B-III-1; lane 5: A-II-2) but absent in normal controls (lane 1) and patients with dilated cardiomyopathy unrelated to LMNA defects (lane 4).