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Figure 1 Hematoxylin-eosin staining in left ventricular biopsies (original magnification x50) before and after left ventricular assist device (LVAD) support. (A) Before LVAD support, there were hypertrophic myocytes of varying nuclear sizes, with vacuolization and interstitial fibrosis. (B) After LVAD support, the myocytes showed less hypertrophy and vacuolization, together with a decrease in myocyte size and an increase in interstitial fibrosis.