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Figure 5 Effect of N-2-mercaptopropionyl glycine (MPG) on transverse aortic constriction (TAC)-induced changes in antioxidant enzyme activities. One week after the operation, mouse hearts were homogenized and subjected to superoxide dismutase (SOD), glutathione peroxidase (GSHPx), and catalase activity assays (n = 4). Control sham = vehicle-treated sham-operated mice; control TAC = vehicle-treated TAC-operated mice; MPG sham = MPG-treated sham-operated mice; MPG TAC = MPG-treated TAC-operated mice. Data are expressed as mean ± SEM. Two-way ANOVA indicated significant difference between TAC versus sham-operated mice, but not vehicle and MPG-treated mice in SOD and GSHPx activities without significant interaction. There were no significant differences in catalase activity between TAC and sham-operated groups and between vehicle and MPG-treated groups.