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Figure 4 Median plasma levels of plasmin-antiplasmin (PAP) before, during, and after unfractionated heparin (UFH) and dalteparin treatment. Black diamond = UFH; white square = dalteparin. Samples were obtained before treatment start (pre), 24 h after start (on), at discontinuation of UFH or dalteparin treatment (stop) and at 3, 6, 12, 24 and 48 h after discontinuation of treatment (3, 6, 12, 24, 48, respectively). Interquartile range of the values at the various time points was 269.2 for UFH and 292.0 for dalteparin.