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Figure 2 Polymer microspheres that have been delivered to muscle through extravasation points created by microbubble insonation. Groups A–F and a control group (G), in which ultrasound was applied to polymer microspheres (PMs) and a 5% albumin solution, are represented. The PMs are limited to the intravascular space in control specimens. The treatment groups are described in Table 1. The bar indicates 200 µm.