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Figure 1 Example from a Group I dog. (A) Parametric image obtained from microsphere-derived flow during maximal hyperemia indicating hypoperfusion in the left circumflex coronary artery (LCx) territory distal to a non-critical stenosis. The myocardial contrast echocardiography (MCE) image taken early after injection matches this image (B), but the late MCE image (C) matches the infarction (D). In this instance a stenosis was first created and then infarction produced by total occlusion of the artery at the site of stenosis. Reflow was then established with the stenosis remaining unchanged. See text for details.