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Figure 1 Polar map of iodine-123 metaiodobenzylguanidine (123I-MIBG) images and three-dimensional diagram of wavelet analysis of RR interval variability in two representative patients with severe myocardial ischemia provoked during balloon coronary occlusion (BCO). These patients had a substantial fall in left ventricular ejection fraction (≥10%) by BCO. In the patient without cardiac denervation (left), the low frequency (LF) components began to rise at ~60 s and reached a peak at ~100 s after balloon inflation. Similar augmentation of the LF components was found during BCO in the patient with cardiac denervation (right). Inf = balloon inflation; Def = balloon deflation.