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Figure 4 Generation of superoxide anion (O₂^–) in porcine coronary arteries cultured for 48 h in the absence (open bars) or presence of spironolactone (10 nmol/l; closed bars). Generation of O₂^– was determined at baseline and after addition of 100 µmol/l nicotinamide adenine dinucleotide (NADH). *p < 0.05.