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Figure 2 Amalgamated data on plasma volume measurements from the studies by Anand et al. (4) and Feigenbaum et al. (42), as assessed by human serum albumin labeled with radioactive iodine and Evans blue dye dilution method, respectively. Plasma volume was similar in both groups of control subjects. There is, however, a marked difference in plasma volume when comparing stable, well-treated patients with chronic heart failure (CHF) and untreated edematous patients in the two studies. This may reflect an increase in plasma volume in the order of 70% during an episode of decompensated heart failure. White bar = control subjects (4); black bar = edematous patients with CHF (4); dotted bar = control subjects (42); diagonal bar = treated patients with CHF (42).