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Figure 2 Frequency of combined end points within 12 months in congestive heart failure patients with (black bars) and without (white bars) beta-blocker treatment, stratified by frequently applied cut-off values for peak oxygen consumption (peakVO2) and left ventricular ejection fraction (LVEF) or by tertiles of norepinephrine and N-terminal pro-brain natriuretic peptide (NT-proBNP) (all p < 0.05).