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Figure 1 (A) Estimated location and extent of electrophysiologically abnormal substrate due to infarction. The epicardium is displayed in three partially overlapping views, viewed from the right posterolateral, anterior and left posterolateral aspects of the torso. The right ventricle (RV) and left ventricle (LV) are labeled. The left anterior descending coronary artery (LAD) and posterior descending coronary artery (PDC) are shown as thick black lines. Gray regions outlined by solid lines define regions with pure Q-wave electrograms during right atrium (RA) pacing. Gray regions outlined by dashed lines define regions with Q-wave electrograms containing superimposed sharp deflections indicating islands of local activation. Representative electrograms during RA pacing are shown on the heart to illustrate the electrogram morphologies in each region. The horizontal dashed black line marks the estimated level of the tissue slice presented in Figures 2 and 4. Top row shows measured data. Bottom row shows noninvasively reconstructed data. (B) Shows electrograms from approximately corresponding locations measured by epicardial-sock electrodes in direct contact with the epicardium (left) and by rod-tip electrodes on the epicardial envelope (right). Numbers correspond to the numbered locations on the heart views in (A).