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Figure 1 These end-diastolic echocardiographic images were obtained in the apical four-chamber view before device implantation (left) and after six months of CRT (right), where a volume reduction is demonstrated. The endocardial borders were manually delineated, and the LV cavity area surrounded by these borders was used for LV volume calculation, as explained in the text. Note the reduction in end-diastolic volume and the reduced sphericity of the LV shape in the right image.