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Figure 5 Positive isovolumic contraction (IVC) velocity in the ischemic region throughout the experiment and its correlation with the transmural extent of necrosis (TEN). (a) Different positive IVC velocity values were found in walls with small and large transmural infarcts during ischemia and reperfusion. (b) To compensate for the large variation in positive IVC velocity between animals, the values at reperfusion were normalized to baseline. Normalized positive IVC velocity highly correlated with TEN. The line of regression is indicated.