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Figure 4 Intimal thickening in rats immunized with heat shock protein (Hsp) 70. Rats were immunized and boosted with Hsp70, bovine serum albumin (BSA) or phosphate-buffered saline (PBS) (control). Two weeks after boost, balloon injury was applied to carotid arteries of both groups. Morphometric evaluation of intimal (A) and medial (B) area were performed using PhotoShop software. The ratio of intima to medial area was also calculated (C). Values represent mean ± SD of all animals in each group. *p = 0.001 as compared with control.