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Figure 1 Kinetics of anti-heat shock protein (Hsp) 70 antibody production. Rats immunized with Hsp70, bovine serum albumin (BSA) or control were bled before (t = 0), 10 days after primary immunization (t = 1), at the time of injury (t = 2) or at sacrifice (t = 3). Anti-Hsp70 antibody levels were determined by enzyme-linked immunosorbent assay. Values represent mean ± SEM of OD from all animals in each group. Upward-pointing solid triangle = BSA; downward-pointing solid triangle = control; solid circle = Hsp70.