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Figure 1 Collagen-induced platelet-derived electrical currents (A) and intraplatelet cyclic guanosine 3',5'-monophosphate (cGMP) levels (B) before and after vitamin C administration in nonsmokers (n = 10) and smokers (n = 11). Collagen-induced platelet aggregation before (C) and after (D) vitamin C administration in nonsmokers (n = 10) and smokers (n = 11). Open bars = nonsmokers; solid bars = smokers; NS = nonsignificant.