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Figure 1 Adjusted relative risks of cardiovascular events according to increasing quartiles of lipoprotein-associated phospholipase A₂ (Lp-PLA₂) and C-reactive protein (CRP) compared to the lowest quartile. The error bars indicate the 95% CIs. The p values are for the highest quartile of plasma marker compared to the lowest quartile. These models were adjusted for random assignment to aspirin and vitamin E and for the following risk factors: low-density lipoprotein and high-density lipoprotein cholesterol, body mass index, a history of hypertension, a history of diabetes, a parental history of myocardial infarction, frequency of exercise and current use of hormone replacement therapy.