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Figure 2 Comparison between exercise capacity and oxidative capacity of vastus lateralis muscle. The maximal adenosine diphosphate (ADP)-stimulated respiration rate of the saponin-skinned fibers (maximal tissue oxygen uptake [Vmax], µmol O2·min–1·g–1 dry weight tissue, left panel) were identical between patients with chronic heart failure (CHF) (open bars) and sedentary controls (SED) (hatched bars), both differing from active controls (ACT) (black bars). The peak oxygen uptake ([VO2 peak] ml·min–1·kg–1, middle panel) and the O2 uptake at the ventilatory threshold ([VO2 at VT] ml·min–1·kg–1, right panel), representing exercise capacity, highly differed among groups in the order CHF < SED < ACT.