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Figure 2 Changes in coronary blood flow caused by enalaprilat at perfusion pressures of 30, 40, 50 and 60 mm Hg (mean values ± SEM). a, Baseline (n = 11). b, After rapid pacing for three weeks (3W, n = 11). c, After rapid pacing for five weeks (5W, n = 5). After three weeks of rapid pacing, enalaprilat significantly increased coronary blood flow at all perfusion pressures, whereas the increase was attenuated, but still significant, after five weeks of rapid pacing. Control indicates before administration of enalaprilat; enalaprilat indicates after administration of enalaprilat; LV = left ventricular mass.