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Figure 4 Examples of percent myocardium with fixed and reversible perfusion defects, which varies as a function of time in medically treated subjects. (A) A subject with a variability index (VI) of 9.5 (refer to the equation in Methods), approximately equal to mean VI for the entire group of subjects. (B) A subject with a VI of 5.0, significantly less than the mean VI for the group. (C) A subject with a VI of 20, significantly greater than the mean VI for the group. Note that dramatic improvements (complete resolution) in the amount of ischemia were observed sometimes.