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Figure 4 Effect of exogenous administration of norepinephrine (NE) and angiotensin II (Ang II) on activation of the MAPK pathways. Representative autoradiograms for each of the three major MAPK pathways are shown. The increase in ERK and JNK activity in the hearts of Dbh^–/– mice after infusion of norepinephrine and angiotensin II was equal to or greater than that of the control hearts.