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Figure 2 Relationship between pressure load and induction of cardiac hypertrophy for all banded mice. The index of LV mass (LVW/BW) is plotted against the trans-stenotic systolic pressure gradient produced by TAC for all of the banded control (n = 17, solid circles) and Dbh^–/– (n = 17, open circles) animals. Linear regression analysis was significant for the control mice (y = 0.0286x + 2.8325, r = 0.66, p < 0.01 by ANOVA), but not for the Dbh^–/– mice (0.0032x + 3.2665, r = 0.20, p = NS). The slopes of the two regression lines were significantly different (p < 0.005) by multivariate ANOVA.