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Figure 5 Frequency of cyclic flow variations (CFVs) (cycles/hour) in carotid arteries transfected with retro-tissue factor pathway inhibitor (TFPI) (A) and carotid arteries transfected with retro-green fluorescent protein (GFP) (B). After induction of the recombinant proteins with doxycycline, CFVs were completely inhibited only in retro-TFPI transfected vessels, although they remained unchanged in the contralateral arteries transfected with retro-GFP. Each dot represents one animal.