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Figure 2 Relationship between the log insulin-like growth factor-I/growth hormone (IGF-I/GH) ratio (from a single sample in the morning) and mean (A) and peak (B) GH levels in 8-h overnight blood samples (study 2). **p < 0.01 vs. control subjects. (C) Relationship between baseline GH-binding protein (BP) levels and the IGF-I response to GH (2 IU/day for 24 h) in nine patients with chronic heart failure (CHF) (study 2) (polynomial correlation: r = 0.90, p = 0.006).