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Figure 3 (A) Increase in color Doppler signal intensity and velocity flow map during adenosine infusion. (B) Coronary angiogram of a patient with 95% stenosis of the left anterior descending coronary artery (LAD), and corresponding transthoracic rest and hyperemic Doppler velocities, with a damped diastolic coronary flow reserve (CFR) of 0.7 due to a decrease in peak diastolic velocity from 30 to 21 cm/s. (C, D) Pre-stenting and post-stenting coronary angiograms of a patient with 85% stenosis of the proximal LAD, and corresponding transthoracic Doppler velocities, with a diastolic CFR of 1.4 on the day before stenting (C), increasing to 2.5 after the procedure (D). Of note, the post-procedural increase in diastolic CFR is due to a reduction in rest and an increase in hyperemic velocity, as compared with pre-stenting values.