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Figure 6 Effects of chronic treatment with the angiotensin-converting enzyme inhibitor ramipril (1 mg/kg/day), the AT1 receptor antagonist valsartan (10 mg/kg/day) and the AT2 receptor antagonist PD 123319 (30 mg/kg/day) on Na+-dependent HCO3–-independent net H+ influx (NHE activity; A) and Na+ and HCO3–-dependent net H+ influx (NBC activity; B) in endocardial tissue preparations seven days after myocardial infarction compared with sham-operated and placebo-treated animals with myocardial infarction. *p < 0.05 compared with sham operation; #p < 0.05 compared with placebo-treated myocardial infarction. Data represent mean ± SEM, n = 10 to 12.