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Figure 4 Thrombin-induced platelet aggregation during the treatment period relative to the pre-treatment period, as determined by whole-blood aggregometry in control dogs and dogs treated with intravenous dipyridamole, inhaled nitric oxide (NO) and the combination of intravenous dipyridamole with inhaled NO (n = 4 dogs in each group). Data are expressed as the mean value ± SEM. *p < 0.05, NO plus dipyridamole versus each of the other groups.